Information and support For professionals Women 'at risk' of developing abnormal thyroid function in conception and pregnancy Certain groups of women have a higher risk of developing abnormal thyroid function during pregnancy. If women are in of these ‘at risk’ groups, check their thyroid levels in conception and at presentation. Who is at risk? History of thyroid disease or surgery Autoimmune conditions with obstetric complication Previous late pregnancy loss Previous thyroid surgery Type 1 diabetes mellitus Stillbirth Goitre Systemic Lupus Erythematosus Second trimester miscarriage Thyroid nodule Anti-Ro/Anti-La positivity Two miscarriages or more Previous overt or subclinical thyroid dysfunction Anti-phopholipid syndrome Subfertility Previous thyroiditis Positive TPO antibodies Previous radioiodine ablation Taking medication which disrupts thyroid function e.g. lithium, amiodarone Previous head/neck irradiations Cardiac dysrhythmia (irrregular heartbeat) Significant weight loss Enlarged thyroid gland Thyroid nodule Read the RCOG Green-top guideline on the Management of Thyroid Disorders in Pregnancy Manage Cookie Preferences Please ensure Javascript is enabled for purposes of website accessibility